Adenosine A2A and metabotropic glutamate receptors interactions: role in Parkinson

Abstract

Event Abstract Back to Event Adenosine A2A and metabotropic glutamate receptors interactions: role in Parkinson Marianne Amalric1* and S. Lopez1 1 UMR6155 CNRS – Universite de Provence, Laboratoire de Neurobiologie de la Cognition, France Adenosine A2A receptors form heteromeric complexes with metabotropic glutamate (mGlu) receptors of subtype 5 and co-aggregate and co-internalize with DA D2 receptors following prolonged stimulation, suggesting a functional interaction between these receptors to regulate basal ganglia function. Recent clinical trials report beneficial effects of adenosine A2A receptor antagonists in the treatment of Parkinson Keywords: 6-hydroxydopamine, Basal Ganglia, motor behaviour, Reaction Time Conference: 3rd Mediterranean Conference of Neuroscience , Alexandria, Egypt, 13 Dec - 16 Dec, 2009. Presentation Type: Oral Presentation Citation: Amalric M and Lopez S (2009). Adenosine A2A and metabotropic glutamate receptors interactions: role in Parkinson. Front. Neurosci. Conference Abstract: 3rd Mediterranean Conference of Neuroscience . doi: 10.3389/conf.neuro.01.2009.16.086 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 20 Nov 2009; Published Online: 20 Nov 2009. * Correspondence: Marianne Amalric, UMR6155 CNRS – Universite de Provence, Laboratoire de Neurobiologie de la Cognition, 13331 Marseille, France, marianne.amalric@univ-provence.fr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Marianne Amalric S. Lopez Google Marianne Amalric S. Lopez Google Scholar Marianne Amalric S. Lopez PubMed Marianne Amalric S. Lopez Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page.