ADENOMATOID ODONTOGENIC TUMOR, THE REPORT OF THREE CASES

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Adenomatoid odontogenic tumor (AOT) is a rare benign odontogenic tumor. AOT represents 3-7% of all odontogenic tumors. First described by Steensland in 1905 and later by Philipsen and Bin in 1969, AOT is an encapsulated tumor composed by odontogenic epithelium with duct-like structures. Radiographically, it commonly appears as a pericoronal unilocular radiolucency associated with an impacted tooth, more often the maxillary canine. Frequently, the lesion shows focal calcifications. Most cases are discovered in the second decade of life. Some authors have considered AOT as a hamartoma rather than a neoplastic process. A peripheral variant has been described. Here, we report three cases of AOT to illustrated the benign course of this tumor. Cases The three cases were found in females at the age of 15, 18 and 33 years. One case was discovered the mandible as periapical lesion and two cases associated with impacted maxillary canines. All cases show well-defined mixed radiolucent and radiopaque appearance. Root resorption was not observed in the mandibular case. Slow growing was reported in all cases. An excisional biopsy was done in the three cases. Microscopically, all cases revealed an encapsulated tumor compose of sheets of solid basaloid epithelium with duct-like spaces. Cystic and solid patterns with dystrophic calcification were also observed. No recurrence has been reported. Conclusion Although, the mandibular case was located in an uncommon location and showed an atypical appearance, all cases demonstrated an indolent behavior. These cases confirm the benign nature of this tumor.