Abstract

Adenoid Cystic Carcinoma (ACC) is a rare tumor constitutes for less than 1% of head and neck malignancies and 10% of all salivary gland tumors. Palate is the most common site to be involved in the oral cavity followed by parotid gland and submandibular gland. They are usually asymptomatic, slow growing, characteristically shows infiltrative growth and perineural invasion. This paper reports a case of Adenoid Cystic Carcinoma in a 35 year old female man reported with a swelling on the left side of palate involving the hard and soft palate since 8 months which was diagnosed histopathologically and review of literature of the peculiar clinical, and histopathological features.

Highlights

  • Adenoid cystic carcinoma is a malignant neoplasm that may affect either the major or minor salivary glands of the oral cavity [1,2]

  • In1859, first described Adenoid Cystic Carcinoma (ACC) under the name "cylindroma", for its cribriform appearance formed by tumor cells with cylindrical pseudolumina or pseudospaces and described that ACC had a "great tendency to recur [3]." It accounts for about 5% to 10% of all salivary gland neoplasms, representing 2% to 4% of malignant occurrences of the head and neck area

  • Tumor is graded according to Szanto et al [8] cribriform or tubular, less than 30% solid, or greater than 30% solid

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Summary

Introduction

Adenoid cystic carcinoma is a malignant neoplasm that may affect either the major or minor salivary glands of the oral cavity [1,2]. It was first described by three Frenchmen (Robin, Lorain, and Laboulbene) in two articles published in 1853 and 1854. A 35 year old female patient came to the department of oral medicine, diagnosis and radiology with a chief complaint of swelling in upper back jaw region since 8 months She presents with history of difficulty in mastication and deglutition. An incisional biopsy was performed under local anesthesia and was subjected to histopathological examination It shows isomorphic basoloid tumor cells in cribriform pattern with eosinophilic material (10x) (Figure 3). A diagnosis of Adenoid Cystic Carcinoma (cribriform pattern) was established

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