Abstract
Adenoid Cystic Carcinoma of the Lacrimal Gland
Highlights
adenoid cystic carcinomas (ACCs) can occur in other exocrine glands of the body
The tumor occurs in all age groups
Authors disclose any relationship with a commercial company that has a direct financial interest in subject matter or materials discussed in article
Summary
Nur Khatib, MDa,*,1, Ioana Catalina Ionescu, MD, PhDa,, Daniel Briscoe, MDb, Peerooz Saeed, MD, PhDa aOrbital Center, Department of Ophthalmology, Amsterdam University Medical Centers, Meibergdreef 9, Amsterdam 1105 AZ, the Netherlands; bOphthalmology Department, HaEmek Medical Center, Afula, Israel. Keywords Adenoid cystic carcinoma Lacrimal gland Pathology Immunohistochemistry Treatment approach Key points Despite the rarity of lacrimal gland adenoid cystic carcinoma (LGACC), it is the most common malignant epithelial cancer of the lacrimal gland, with a low survival rate. The combined approach of globe-sparing surgery with adjuvant radiotherapy is considered to have a favorable visual and functional outcome with good local control rates. Future randomized clinical trials are crucial to determine the outcomes between conservative and radical surgical protocols. The therapeutic strategy of LGACC relies on a strong multidisciplinary collaboration between an orbital surgeon, radiotherapist, pathologist, and oncologist
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