Adenoid Cystic Carcinoma of the Cervix: Case Report

Caroline Ribeiro,Valentino Antonio Magno,Giovana Fontes Rosin,Cristiano Degasperi,Isabella Osorio Wender,Márcia Appel Binda

doi:10.4236/ojog.2019.96086

Abstract

Adenoid cystic carcinoma (ACC) is usually an epithelial neoplasm of the salivary glands but can also occur in the lacrimal glands and the mucous glands of the respiratory tract, breasts and skin. Very rarely, it may affect the uterine cervix. We report here a case of a woman with postmenopausal bleeding for 7 months, who on physical examination presented with a vegetative and friable tumor lesion in the uterine cervix, measuring about 5 cm in diameter. The abdominal and pelvic computed tomography scans showed a hypodense and heterogeneous mass in the cervix and uterine isthmus. Histopathological examination and immunohistochemical assays confirmed the diagnosis of ACC. The different pathological aspects, therapeutic options and prognostic factors of ACC are discussed.

Highlights

Adenoid cystic carcinoma (ACC), was first described between 1853 and 1854 by three French scientists: Robin, Lorain and Laboulbène [1]
We report here a case of a woman with postmenopausal bleeding for 7 months, who on physical examination presented with a vegetative and friable tumor lesion in the uterine cervix, measuring about 5 cm in diameter
ACC is an uncommon form of malignant neoplasm that arises in secretory glands, commonly associated with major and minor salivary gland neoplasms; it can occur in a variety of other sites such as the respiratory tract, breasts and skin

Summary

Introduction

Adenoid cystic carcinoma (ACC), was first described between 1853 and 1854 by three French scientists: Robin, Lorain and Laboulbène [1]. The first case of a cervical ACC was only reported in 1949 by Paalman and Counseller [2]. ACC is an uncommon form of malignant neoplasm that arises in secretory glands, commonly associated with major and minor salivary gland neoplasms; it can occur in a variety of other sites such as the respiratory tract, breasts and skin. This neoplasm is defined by its distinctive histological appearance [1]. We report an extremely rare case of a patient who was diagnosed with cervical ACC. The patient had given her consent for the case report to be published

Case Report

Discussion

Findings

Ribeiro et al DOI

Conclusions