Abstract

A 66-year-old female patient, melanoderma, non-smoker/non-alcoholic, was referred by the dentist to stomatology clinics due to a palatal lesion. She had noticed the lesion 4 years before the consultation, but reported that she only begun to have painful symptoms more recently. During intraoral examination, multiple nodules, with irregular contours, were observed on hard and soft palate. The mucosa that recovered the lesion presented areas with aspect close to normal, others erythematous and others ulcerated. With a diagnostic hypothesis of malignant salivary gland neoplasia, an incisional biopsy was performed. Histopathological examination revealed a malignant salivary gland neoplasm with cells of 2 differentiations, luminal and myoepithelial, forming tubular and cribriform structures. Immunohistochemistry confirmed both the differentiations and the final diagnosis was adenoid cystic carcinoma. These are rare malignancies of salivary glands that usually are slow growing but show local invasion and recurrences with poor long-term survival.

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