Abstract
Introduction: Adenocarcinoma in situ (AIS) is considered the precursor of cervical adenocarcinoma. Its incidence is increasing and is usually found in younger women with average age 35.8 years. The management of this lesion is complicated since recommendations vary from radical hysterectomy to more conservative treatments like cone biopsy in women who want childbearing. Fertility spearing management in well-selected patients has shown comparable oncological outcomes as more radical treatments, with the status of the excision margins being the hallmark for the prediction of disease.
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