Adenocarcinoma containing lepidic growth.

Abstract

Lepidic growth adenocarcinoma is defined as tumor cells proliferating along the surface of intact alveolar walls without stromal or vascular invasion pathologically (1). The traditional viewpoint has been that of Noguchi et al. (2) who demonstrated that localized bronchioloalveolar carcinoma (LBAC) showed replacement growth of alveolar-lining epithelial cells with a relatively thin stroma, that LBAC with foci of structural collapse of alveoli were in situ peripheral adenocarcinoma, and that lung cancer patients with these LABCs achieved 100% survival after lobectomy.