Abstract

After morphologic and histochemical analysis of an adenoameloblastoma excised from the left maxilla of a 17-year-old Negro girl, the following conclusions were drawn: 1. 1. When there are morphologic changes of the neoplastic parenchyma with glandular ductlike structures whose cylindrical cells resemble ameloblasts, the lesion must be diagnosed as adenoameloblastoma. 2. 2. The calcifications in the adenoameloblastoma are dystrophic formations which arise in the eosinophilic sites that result from erythrocytic degeneration and agglutination, as well as from the products of secretion, rich in chondroitin sulfate, elaborated by the epithelial cells. 3. 3. These calcifications should not be interpreted as an assay of amelogenesis. 4. 4. The neoplastic parenchyma is low in glycogen, but in the cell cytoplasm and intercellular spaces there is a mixture of glycoproteins and/or mucoproteins, carboxylated and sulfated mucopolysaccharides, and free amino radicals. 5. 5. The adenoameloblastoma is an odontogenic tumor that may arise from the embryonic odontogenic oral epithelium of the cystic epithelium or from the epithelial rests of Malassez.

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