Abstract

Lattice structures are widely employed in bone scaffolds to obtain high porosity with interconnected pores and high surface area-to-volume and strength-to-weight ratios. Here, 21 lattice-based scaffold architectures were modeled using implicit functions and additively manufactured using epoxidized soybean oil-based resin. The porosity of the scaffolds ranged from 53.42% ± 1.16% to 98.28% ± 0.75%. Scaffolds with the lowest overall porosity (Group 1) exhibited the highest compressive strength. The compressive strength of eighteen different three-dimensional scaffold designs was compatible with that of human trabecular bone. The results and methodology presented here can facilitate the mathematical design of complex porous scaffolds for bone tissue engineering.

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