Abstract
Introduction: Radiofrequency ablation (RFA), a palliative therapeutic option for solid hepatic tumors, stimulates localized and systemic anti-tumor cytotoxic T cells. We studied how far addition of CpG B oligonucleotides, toll like receptor (TLR) 9 agonists, may increase the anti-tumoral T cell response of RFA in the highly aggressive VX2 hepatoma.
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