Abstract

A table presenting all meta-analyses done. 'Analysis' refers to the the type of data used in each meta-analysis, as this was explained in Methods. 'Studies' refers to the number of studies included within each meta-analysis. Columns 'HR' and '95 % CI' refer to the summary Hazard Ratio (HR) of each meta-analysis with its 95 % Confidence Interval (CI) (lower and upper limit). 'Tau' refers to the squared root of the estimate of between-study variance in each of our random-effects meta-analyses. Columns 'I and '95 % CI' refer to a measure of between-study heterogeneity and its corresponding 95 % CI. 'Q-statistic' and its 'P-value' refer to Cochran's Q measure of heterogeneity with its p-value. 'Observed', 'Expected' and 'P-value (binomial)' refer to the observed and expected amount of statistically significant results and the comparison between the two, as this was described in Methods. (XLSX 50.7 kb)

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