Additional file 1: of Long-term exposure to insulin and volumetric mammographic density: observational and genetic associations in the Karma study

Abstract

Table S1. Prescriptions of insulin and insulin analogs dispensed in the year prior to study entry in T1D and T2D patients. Table S2. Prescriptions of glucose-lowering medication dispensed in the year prior to study entry in T2D patients not receiving insulin therapy. Table S3. Single-nucleotide polymorphisms included in the insulin genetic score. Table S4. Descriptive characteristics of insulin-treated T2D patients and non-insulin-treated T2D patients. Table S5. Geometric means and percentage differences of volumetric mammographic density comparing glargine insulin users to non-glargine insulin users (case only analyes). Table S6. Geometric means and percentage differences of volumetric mammographic density comparing insulin-treated T2D patients to non-insulin treated T2D patients. Table S7. Geometric means and percentage differences of volumetric mammographic density comparing insulin-treated T1D and T2D patients to age-matched individuals without diabetes by insulin treatment duration. Table S8. Geometric means and percentage differences of volumetric mammographic density by treatment duration in insulin-treated T1D patients (case only analyses). Table S9. Associations of fasting insulin single nucleotide polymorphisms with volumetric mammographic density. (DOCX 88 kb)