Addition of Braun Enteroenterostomy – Impact on early outcomes in Pancreaticoduodenectomy

Abstract

Background: Morbidity following Pancreaticoduodenectomy still remains high.Few studies have shown decrease in morbidity with the addition of Braun enteroenterostomy (BE). Our aim was to determine any possible benefit with addition of BE to the standard reconstruction after pancreaticoduodenectomy Methods: All patients who underwent pancreaticoduodenectomy from Feb2011 to July2016 were included.They were randomized to undergo either Standard reconstruction (Group A)or with addition of Braun enteroenterostomy (Group B). Outcomes were compared between 2 groups and the results were analyzed. P value of <0.05 was considered significant Results: 104 patients were included.Group A included 56 patients who underwent standard reconstruction and Group B had 48 patients with addition of Braun enteroenterostomy. The demographic profile,tumor characteristics, and biochemical profile were similar in 2 groups. Mean operating time, Intraoperative blood loss and requirement for transfusion were similar.The incidence of pancreatic fistula (POPF) did not differ significantly in 2 groups (14/56,25% in group A vs. 8/48,16.6% in group B; p= 0.42). The Incidence of DGE was not statistically different in 2 groups (20/56,35.7% in group A vs. 12/48,25% in group B;p=0.77). Infection rates were similar in two groups. Mean hospital stay was similar in both groups (11.2 in group A vs. 10.7 days in group B; p=0.68) Conclusion: The outcomes of patients after pancreaticoduodenectomy were not altered by addition of Braun enteroenterostomy