Abstract

N2-Acetyl-8-bromoguanine has been found to react readily with 2,3-dihydrofuran in DMF in the presence of acid catalyst at room temperature to give 9-(tetrahydrofuryl-2)-8-bromo-N2-acetylguanine in high yield. The structures of this compound and its deacetylated derivative were assigned by H and C NMR spectroscopy.

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