Addition d'organometalliques allyliques et d'organolithiens satures aux enynes conjugues, simples et fonctionnels

Abstract

Reactive organometallic compounds such as allyl-zinc, -magnesium, and -lithium and saturated lithium compounds are shown to bring about readily an addition reaction with simple and α-substituted conjugated enynes RCCCHCHCH 2 R′ [R = H, CH 3;R′ = alkyl, OH, OC 4H 9, NHC 2H 5, N(C 2H 5) 2]. The regioselectivity of the reaction depends on the nature of the metal atom in the organometallic compound. The reaction takes place also in certain cases with organometallic vinyl compounds.