Abstract
SEE CORRESPONDING ARTICLE ON PAGE 1051 Negative Urgency Exacerbates Relapse to Cocaine Seeking After AbstinenceBiological PsychiatryVol. 91Issue 12PreviewThe mechanisms through which drug-cue–induced negative affective states are involved in relapse have not been defined. We tested the hypothesis that in individuals having developed a dorsolateral striatum (DLS)–dependent cue-controlled cocaine-seeking habit, the loss of the opportunity to enact the drug-seeking response during abstinence results in an urge to act that exacerbates relapse severity mediated by negative urgency. Full-Text PDF
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