Added Value of Thoracic Magnetic Resonance Imaging in the Differential Diagnosis Between Peripheral Lung Cancer and Progressive Massive Fibrosis of Coal Silicosis

Abstract

To compare the thoracic magnetic resonance imaging (TMRI) features between peripheral lung cancer (PLC) and progressive massive fibrosis (PMF) of coal silicosis (CS), and to excavate information of differential diagnostic value. 68 patients with PLC (68 lesions) were selected as lung cancer group (LCG), and 50 patients with PMF of CS (78 lesions) were selected as coal silicosis group (CSG). TMRI was performed in both groups, and T1-weighted imaging (T1WI), T2-weighted imaging (T2WI) and Spectral pre-saturated inversion recovery (SPIR) were used. The differences and characteristics of TMRI between the two groups were analyzed. 55 cases of pulmonary masses (PM) in LCG showed iso-signal intensity on T1WI (80.9%), and 63 cases showed high-signal intensity on T2WI and SPIR (92.6%); 65 cases of PMF in CSG showed iso-signal intensity on T1WI (83.5%), and high-signal intensity on T2WI and SPIR was found in 4 cases (5.1%), but 67 cases showed low-signal intensity (85.9%). PMF in CSG with high-signal intensity on T2WI and SPIR were significantly lower than PM in LCG(P < 0.1). Compared with TMRI of PLC showed high-signal intensity on T2WI and SPIR, PMF in CS showed low-signal intensity on T2WI and SPIR. This feature is of important significance in differential diagnosis.