Abstract
Information on the long term efficacy and tolerability of vigabatrin in children is scarce. This open, 4-year add-on study reports the effects of vigabatrin in 22 children aged 26 to 220 months with refractory epilepsy. The 22 children entered this 4-year long term study after 2 months of add-on vigabatrin at a fixed dose, and two 2-month periods of vigabatrin adjustment.
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