Adaptive Filtering with Fitted Noise Estimate (AFFiNE): Blink Artifact Correction in Simulated and Real P300 Data.

Abstract

(1) Background: The electroencephalogram (EEG) is frequently corrupted by ocular artifacts such as saccades and blinks. Methods for correcting these artifacts include independent component analysis (ICA) and recursive-least-squares (RLS) adaptive filtering (-AF). Here, we introduce a new method, AFFiNE, that applies Bayesian adaptive regression spline (BARS) fitting to the adaptive filter's reference noise input to address the known limitations of both ICA and RLS-AF, and then compare the performance of all three methods. (2) Methods: Artifact-corrected P300 morphologies, topographies, and measurements were compared between the three methods, and to known truth conditions, where possible, using real and simulated blink-corrupted event-related potential (ERP) datasets. (3) Results: In both simulated and real datasets, AFFiNE was successful at removing the blink artifact while preserving the underlying P300 signal in all situations where RLS-AF failed. Compared to ICA, AFFiNE resulted in either a practically or an observably comparable error. (4) Conclusions: AFFiNE is an ocular artifact correction technique that is implementable in online analyses; it can adapt to being non-stationarity and is independent of channel density and recording duration. AFFiNE can be utilized for the removal of blink artifacts in situations where ICA may not be practically or theoretically useful.