Abstract
To investigate the relationship between adaptation time and the parameters of electroretinography (ERG) and pupillography in healthy subjects. Forty-six eyes of 23 healthy women (mean age 21.7years) were enrolled. ERG and pupillography were tested in each of the right and left 23 eyes, respectively. ERG with a skin electrode was used to determine amplitude and implicit time by the records of rod-, flash-, cone-, and flicker-responses with white light (0.01-30cds/m2). Infrared pupillography was used to record the pupillary light reflex to 1-s stimulation of red light (100cd/m2). Cone- and flicker- (rod-, flash- and pupil) responses were recorded after light (dark) adaptation at 1, 5, 10, 15, and 20min. Amplitude (µV) was significantly different between 1min and ≥ 5 or ≥ 10min after adaptation in b-wave of cone- or rod-response, respectively. Implicit time (ms) differed significantly between 1min and ≥ 5min after adaptation with b-wave of cone- and rod-response. There were significant differences between 1min and ≥ 10 or ≥ 5min after dark adaptation in parameter of minimum pupil diameter (mm) or constriction rate (%), respectively. Cone-driven ERG can be recorded, even in 5min of light adaptation time without any special light condition, whereas rod-driven ERG and pupillary response results can be obtained in 10min or longer of dark adaptation time in complete darkness.
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More From: Documenta ophthalmologica. Advances in ophthalmology
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