Abstract

The thyroidal 131I-uptake of inhabitants of Buenos Aires is higher than that obtained in areas where iodine provision is adequate. The conversion ratio and the thyroid clearance of iodine are also high. Urine iodine and iodine content of water are low, as compared with values obtained in areas where there is no endemic goiter. Young men born and raised in Buenos Aires city have a 2.35% incidence of goiter of degree I, according to the classification of WHO. When thyroid enlargements intermediate between degree 0 and I were taken into account, a further 17.9% of thyroid enlargement was recorded. These data point to a low iodine intake in Buenos Aires, the magnitude of which parallels that of the metabolic and morphologic changes in the thyroid gland. These changes, in turn, suggest that some adaptive mechanisms have maintained normal hormonal secretion. The suggestion is made that the classification of goiter provided by WHO should be revised, since it does not record goiters of moderate although significant size.

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