Abstract
The activity of the retinal dopamine neurons was studied in light-adapted rats exposed to darkness for periods ranging from 10 min to 15 h. Dihydroxyphenylalanine (DOPA) accumulation, following inhibition of l-aromatic amino acid decar☐ylase with NSD-1015, was used as an index of dopamine neuronal activity. After only 10 min of darkness, DOPA accumulation had decreased to levels found in rats dark-adapted for 15 h.
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