Abstract

Objective To adapt and validate the Malay version of Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) questionnaire. Design The OAKHQOL was adapted into Malay version using forward-backward translation methodology. It was then validated in a cross-sectional study of 191 patients with knee osteoarthritis (OA). Patients completed the OAKHQOL and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Confirmatory analysis, reliability analysis, and Pearson correlation test were performed. Results The new five-factor model of 28 items demonstrated an acceptable level of goodness of fit (comparative fit index = 0.915, Tucker-Lewis index = 0.905, incremental fit index = 0.916, chi-squared/degree of freedom = 1.953, and root mean square error of approximation = 0.071), signifying a fit model. The Cronbach's alpha value and the composite reliability of each construct ranged from 0.865 to 0.933 and 0.819 to 0.921, respectively. The Pearson correlation coefficient between the OAKHQOL and the WOMAC showed adequate criterion validity. Known groups validity showed statistical difference in body mass index in physical activity, mental health, and pain construct. The pain domain was statistically different between the age groups. Conclusion The Malay version OAKHQOL questionnaire is a valid and reliable instrument to assess health-related quality of life in knee OA patients.

Highlights

  • Osteoarthritis (OA) is the most common disease of joints in adults around the world [1, 2]

  • It was suggested that the SF-36 and WOMAC should be used in combination [8]; they may still fail to capture specific QOL aspects related to hip or knee osteoarthritis

  • Knee Injury and Osteoarthritis Outcome Score (KOOS) is another questionnaire but its assessment is not BioMed Research International limited to quality of life because it includes pain, other symptoms, activity of daily living, sports, and recreational activity measurements [9]

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Summary

Introduction

Osteoarthritis (OA) is the most common disease of joints in adults around the world [1, 2]. There are few validated instruments used in studies to assess health-related QOL in patients with OA . The Lequesne index and Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire, which are more disease-specific, are able to measure only pain and function but not the other domains of QOL such as mental, social, and sexual domains [6, 7]. Knee Injury and Osteoarthritis Outcome Score (KOOS) is another questionnaire but its assessment is not BioMed Research International limited to quality of life because it includes pain, other symptoms, activity of daily living, sports, and recreational activity measurements [9]. The Osteoarthritis Knee and Hip Quality of Life (OAKHQOL) scale questionnaire was developed and validated to measure the impact of knee and hip osteoarthritis on the patient’s QOL

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