Abstract
Strained polycyclic spiro(1-pyrazoline-3,1′-cyclopropanes) react with acetyl or benzoyl chlorides at 0–15 °C regioselectively to give in high yields corresponding 1-acyl-3-(2-chloro-ethyl)-2-pyrazolines. Under the same conditions 6-ethenyl-4,5-diazaspiro[2,4]hept-4-ene gives a mixture of two pyrazolines resulting from the acyl group attack directed at different nitrogen atoms. Bicyclic pyrazolines-2 obtained by acylation of the cycloaddition products of diazocyclopropane with 3,3-disubstituted cyclopropenes transform under the action of hydrogen chloride to 1,4,5,6-tetrahydropyridazines in high yields.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
