Abstract
The preparation of certain 1-[(1,3-Dihydroxy-2-propoxy) methy1] 6-azauracils, acyclic analogues of antiviral DHPG, is described. A number of 6-azauracils were trimethylsilylated and then coupled with 2-chloromethoxypropane to give 1-[(1,3-Dihydroxy-2-propoxy) methy1] 6-azauracils which were debenzylated with either boron trichloride or palladium oxide to yield the title compounds.
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