Abstract

Purpose: To report a case of acute myeloid leukemia with acute vision loss as the initial presenting feature in a young male.Method: A case report.Result: A 25-year-old young man, who has no other significant medical history, experienced sudden blurred vision in the left eye for 3 days. On examination, the best-corrected visual acuity (BCVA) was 6/6.7 in the right eye and counting finger in the left eye. Fundal examination revealed macular hemorrhage in the left eye and multiple white-centered retinal hemorrhages (Roth spots) scattered in the posterior poles of both eyes. Laboratory examinations revealed bicytopenia (red blood cell, 1.12 × 10^6/ l, and platelets, 12 × 10^3/ l). Peripheral blood smear showed blasts with Auer rods. Bone marrow biopsy revealed CD34 positivity. A diagnosis of acute myeloid leukemia M2 was made. After chemotherapy, the Roth spots disappeared and the visual acuity of the left eye recovered to 6/30.Conclusion: Patients with undiagnosed leukemia may initially be referred to an eye clinic. Keeping in mind and careful examinations are necessary.

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