Abstract
Background: Ototoxicity induced by organic solvents has been identified in several groups of workers.Little is known, however, about the effects of organic solvents on the vestibular system.<br />Purpose: The aim of the study was to comprehensively assess the vestibular system and auditory functionsin a worker exposed to organic solvents.<br />Research Design: Both behavioral and physiological auditory and vestibular evaluations wereperformed.<br />Results: No auditory-related findings associated with solvent exposure were found. The vestibulo-ocularreflex gain was abnormal for all semicircular canals with significant catch-up saccades, as measured bythe video head impulse test. The cervical vestibular evoked myogenic potentials was absent in the rightear and small but replicable in the left ear. Ocular vestibular evoked myogenic potential were bilaterallyabsent.<br />Conclusions: The results suggest a case of vestibulotoxicity induced by a long history of organic solventexposure. We suggest that solvent-exposed individuals should be evaluated with a comprehensive batteryof auditory and vestibular tests.<br />
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