Abstract

Methods AMPP is a longitudinal, US-population-based study for which questionnaires were mailed to 24,000 severe headache sufferers and followed annually. Respondents with ICHD-2 migraine were stratified as either CM (>15 headache-days/month) or EM ( half the time. An item response theory (IRT) model used to define scaled treatment optimization scores as function of M-TOQ item set: lower scores=less/problematic optimization; higher scores=greater optimization. The model was expanded to incorporate persons with CM/EM on scaled scores and explored demographic adjustments for age and gender.

Highlights

  • Acute treatment optimization for migraine: results of the American migraine prevalence and prevention (AMPP) study

  • AMPP is a longitudinal, US-population-based study for which questionnaires were mailed to 24,000 severe headache sufferers and followed annually

  • Acute-treatment optimization was measured with MTOQ, a valid/reliable patient-report tool assessing 5 domains: functioning, rapid relief, relief consistency, recurrence risk, tolerability over preceding 4 weeks

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Summary

Introduction

Acute treatment optimization for migraine: results of the American migraine prevalence and prevention (AMPP) study RB Lipton1*, AN Manack2, D Serrano3, DC Buse4 From The European Headache and Migraine Trust International Congress London, UK.

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