Abstract

Respiratory viral illnesses can lead to a wide variety of neurological complications. However, only a few cases of acute transverse myelitis (ATM) following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection have been reported in the literature. Here, we report a case of ATM following SARS-CoV-2 infection in a 57-year-old male patient. The patient presented to the emergency room with lower abdominal pain, urinary retention, bilateral lower limbs weakness, and allodynia for the last four days. One week earlier, he had experienced fever, cough, and shortness of breath. On physical examination, he was vitally stable with sensory loss from the nipples down to the lower limbs bilaterally. His nasopharyngeal polymerase chain reaction for SARS-CoV-2 was positive. MRI of the spine showed an abnormal cord signal extending from the level of the D2 vertebra down to the conus medullaris. The main differential diagnosis was transverse myelitis, and the patient was started on pulse steroids for seven days. After the therapy, the condition of the patient improved with the restoration of power and sensory sensation in his lower limbs. A new MRI of the whole spine one month later showed normal morphology and signal intensity without any abnormal enhancement. The patient was discharged home with almost complete resolution of his symptoms for later follow-up in the clinic.

Highlights

  • Coronaviruses have been linked to illnesses such as the common cold, Middle East respiratory syndrome, and severe acute respiratory syndrome (SARS)

  • Complete blood count (CBC), vitamin B12, folate, and thyroid-stimulating hormone levels were within the normal range

  • The involvement of the gray matter was suggestive of ischemia, and the main differential diagnosis was transverse myelitis

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Summary

Introduction

Coronaviruses have been linked to illnesses such as the common cold, Middle East respiratory syndrome, and severe acute respiratory syndrome (SARS). A new coronavirus, known as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was discovered in China in 2019. COVID-19 is used to prescribe a mixture of clinical symptoms secondary to SARS-CoV-2. There are only a few reported cases in the literature about acute transverse myelitis (ATM) after SARS-CoV-2 infection [1]. Transverse myelitis is an inflammation of one or more spinal cord levels with no concomitant compressive lesions. It is divided into acute and subacute inflammatory myelopathy; the disease can be disabling resulting in motor weakness, sensory deficits, and autonomic dysfunction [2]. We present the case of a 57-year-old male patient who developed ATM secondary to COVID-19 infection

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