Abstract

AbstractPurpose To present three case reports of acute retinal necrosis (ARN) syndrome and discuss the aspects of diagnosis, treatment and prognosis.Methods Retrospective analysis of clinical, laboratory, photographic and angiographic records of three immunocompetent patients with acute retinal necrosis syndrome.Results Two male 22 and 36 years old and one female 25 years old patients had typical clinical symptoms of ARN syndrome: sudden decrease of vision acuity, eye pain, multiple areas of peripheral retinal necrosis, occlusive vasculitis, opticopathia, anterior uveitis and vitritis. Serum Ig G antiviral (VZV, HSV, CMV) titers were the basis for the etiological diagnosis. After applying systemic antiviral and steroid therapy, a rapid improvement of symptoms with the development of pigmentation in the areas of retinal whitening was observed in all patients. Retinal detachment occurred in 2 male patients and was successfully treated.Conclusion Acute retinal necrosis syndrome is one of the vision threatening diseases for immunocompetent patients with poor prognosis. Early diagnosis and urgent antiviral therapy is therefore of vital importance for visual outcomes. Long term follow‐up is necessary due to high risk of retinal detachment.

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