Abstract
Introduction: Reasons for acute renal failure in hospitalized infants were sepsis, hypovolemia, asphyxia, respiratory distress syndrome, surgical interventions and congenital heart defects. The aim of this study was to determine the frequency and main etiologies, and early outcome of neonatal acute renal failure. Materials and Methods: At Intensive Care Unit, Clinical Center Tuzla, from 15. 01. 2013 to 15. 01. 2015 in 21 newborn was diagnosed renal failure, based on the amount of excreted urine and serum creatinine. Results: The prevalence of renal failure was 6.84%, with a higher incidence of female. 33.3% of infants were term neonates. Oliguria was diagnosed in 71.4% of newborns. Sepsis was the most common predisposing factor for the development of renal failure, associated with high mortality. Other causes of renal failure were perinatal hypoxia, RDS, surgical interventions and congenital heart defects. There was a positive correlation between the gestational age of the newborn and serum creatinine. Discussion: Early prevention of risk factors with rapid diagnosis and effective treatment, can affect further outcome of acute renal failure in infants.
Highlights
Reasons for acute renal failure in hospitalized infants were sepsis, hypovolemia, asphyxia, respiratory distress syndrome, surgical interventions and congenital heart defects.The aim of this study was to determine the frequency and and main etiologies, and early outcome of neonatal acute renal failure
The mean duration of hospitalization for each newborn was 10,2 ± 3,2 days.Oliguria was detected in 15 patients (71,4%) and 6 newborns (28,6%), were nonoliguric.The most common causes of ARFin our patients were, in order of prevalence, included sepsis (71,5%), followed by hypoxia secondary to perinatal asphyxia (42,8%), RDS (38%), same such as surgical procedure (38%), and congenital heart disease (23,8%)
Death occurred in 18 patients (36.7%), while 63.3% were discharged with normal renal function (Table 1)
Summary
Reasons for acute renal failure in hospitalized infants were sepsis, hypovolemia, asphyxia, respiratory distress syndrome, surgical interventions and congenital heart defects.The aim of this study was to determine the frequency and and main etiologies, and early outcome of neonatal acute renal failure. Acute renal failure (ARF) is a common problem in the hospitalised newborn at Intensive care unit (ICU) It is the rapid decline in the kidney ability of maintaining homeostasis of water and electrolytes, associated with a reduction of the glomerular filtration rate [1]. Whether pre-renal injury is caused by true volume depletion or decreased effective blood volume, correction of the underlying disturbance will return renal function to normal [3, 4, 5].Considering the high incidence rate of ARF (10–26%) in hospitalized newborns and the high mortality rate of this disease (20–50%), it is one of the most important diseases among ICU patients [2, 3, 4, 5]. The aim of this study wasto determine the frequency and main etiologies of ARF, and early outcome of neonatal ARF
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
