Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly infectious viral pathogen with high morbidity and mortality rate. The infection affects multiple organ systems leading to systemic organ failure. There is an increased incidence of acute kidney injury (AKI) in patients who become critically ill. In the critical care setting, the incidence of AKI has been variable amongst different studies. Patients with acute kidney injury who progress to renal replacement therapy are associated with worse outcomes. We describe a case of a 42-year-old male who presented with hypoxemic respiratory failure secondary to SARS-CoV-2 associated pneumonia. The patient was initially managed with the nasal cannula and then required high flow nasal cannula with worsening hypoxemic respiratory failure, requiring invasive mechanical ventilation. On top of worsening respiratory status, the patient developed new onset renal failure requiring hemodialysis.

Highlights

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused global economic and health implications

  • We describe a case of a 42-year-old male who presented with hypoxemic respiratory failure secondary to SARSCoV-2 associated pneumonia

  • This report addresses a case of a patient with no underlying medical history or chronic kidney disease who progressed to end-stage renal disease, requiring hemodialysis after coronavirus disease 2019 (COVID19) infection

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Summary

Introduction

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused global economic and health implications. This report addresses a case of a patient with no underlying medical history or chronic kidney disease who progressed to end-stage renal disease, requiring hemodialysis after coronavirus disease 2019 (COVID19) infection. The patient complained of a two-day history of shortness of breath and fever. He denied any chest pain, cough, myalgia, or loss of taste or smell. During the first few days of hospitalization, the patient had creatinine levels within normal limits; baseline creatinine is 0.6-.8 mg/dl During his stay in the critical care unit, creatinine levels continued to rise. The patient’s respiratory status continued to deteriorate, requiring a high FiO 2 and positive end-expiratory pressure (PEEP). Full advanced cardiovascular life support protocol was performed; the return of spontaneous circulation was not achieved

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