Abstract
Onset of acute renal failure (ARF) during transfusion of red blood cells is generally attributed to anaphylactic shock or disseminated intravascular coagulation due to an incompatibility of the transfused blood [1], Studies have shown that infusions of stroma-free hemoglobin, inducing hemoglobinuria, caused no evidence of renal failure in animals or in man [2]. We report here a case where a transfusion of accidentally frozen autologous red blood cells resulted in massive hemoglobinuria and severe ARF without evidence of another possible mechanism.
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