Abstract
SUMMARY Different groups of lethally-irradiated and normal control mice were inoculated with a pigmented Pseudomonas (P. aeruginosa), or a non-pigmented Pseudomonas (P. stutzeri), by intraperitoneal and oral routes. Thirty-two of 50 mice receiving P. aeruginosa died within 8 days after irradiation, and 29 of the 32 showed pigmented P. aeruginosa on heart blood culture. Fewer early deaths were seen with oral administration of the organisms than with intraperitoneal administration. Two out of 50 mice given P. stutzeri died within 8 days of exposure to X-rays. Neither showed the organism on heart blood culture. No pigment reversion for cither organism was demonstrated in vivo. These results indicate that P. stutzeri is not involved in the early-death syndrome in X-irradiated mice.
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