Abstract
Benzydamine hydrochloride is a locally acting nonsteroidal anti-inflammatory drug. Benzydamine hydrochloride overdose can cause stimulation of central nervous system, hallucinations, and psychosis. We presented a young man with psychotic symptoms due to benzydamine hydrochloride abuse. He received a total dose of 1000 mg benzydamine hydrochloride with alcohol for its hallucinative effects. Misuse of benzydamine hydrochloride must be considered in differential diagnosis of first-episode psychosis and physicians should consider possibility of abuse in prescribing.
Highlights
Benzydamine hydrochloride (BH) is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anesthetic and analgesic properties for pain relief [1]
In this case report we present a young man that received high dose BH with alcohol and associated psychotic symptoms
In Turkey, BH preparates could be sold without prescription but Ministry of Health of Turkey prohibited selling BH preparates without prescription in 2012 after increased number of abusing cases
Summary
Benzydamine hydrochloride (BH) is a locally acting nonsteroidal anti-inflammatory drug (NSAID) with local anesthetic and analgesic properties for pain relief [1]. Its reported side effects are urticaria, erythema, rash, photosensitivity, bronchospasm, and renal dysfunction. BH’s daily maximum oral usage dose is 200 mg/day. Hallucinations, stimulation of central nervous system, excitation, hyperactivity, paranoia, dry mouth, and convulsions may occur in oral dosages of 500–3000 mg. Recreational use of benzydamine is popular in Poland and Brazil and recently some cases were reported from Turkey [3, 4]. In this case report we present a young man that received high dose BH with alcohol and associated psychotic symptoms
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