Abstract

Acute promyelocytic leukemia (APML) is a myeloid leukemia classified as M3-AML. It is known for its bleeding diathesis, which is predominantly driven by disseminated intravascular coagulation and primary hyperfibrinolysis. However, thrombotic events are relatively less common. A combination of bleeding and thrombotic events is rare and poses a challenge in management. We present a case of acute promyelocytic leukemia complicated by deep venous thrombosis, pulmonary thromboembolism, and hematemesis.

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