Abstract
BackgroundLeptospirosis or Weil’s disease is caused by pathogenic spirochete bacteria called Leptospira. It is considered the most common zoonosis in the world and is usually transmitted by urine of rodents and dogs with an incubation time of 7–14 days. The clinical spectrum ranges from a subclinical infection to a fulminant septic course.Case presentationHere, we report the case of a German patient with acute pancreatitis associated with Leptospira interrogans causing fulminant septic shock. The patient was successfully treated with intravenous antibiotics and left the hospital fully recovered after 18 days.ConclusionsTo our knowledge, this is the first case of leptospirosis with acute pancreatitis as the leading clinical manifestation in Central Europe. Serologic and molecular genetic tests for leptospirosis should be considered, if no other causes for pancreatitis can be identified.
Highlights
Leptospirosis or Weil’s disease is caused by pathogenic spirochete bacteria called Leptospira
We report the case of a German patient, who presented with acute pancreatitis
Acute liver failure with jaundice, hemorrhagic diathesis with purpura and petechiae combined with acute kidney injury accompanied by an odd transient macular, erythematous rash directed to serologic testing for leptospirosis
Summary
This is the first case of leptospirosis with acute pancreatitis as the leading clinical manifestation in Central Europe. Serologic and molecular genetic tests for leptospirosis should be considered, if no other causes for pancreatitis can be identified
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