Abstract
Normal and acutely ischemic myocardium was imaged by dynamic computed transmission tomography (CT) in dogs during injection of contrast material. The rotary fan-beam CT scanner used could obtain 16 sequential, ungated, 3.0-second scans at 13-20-second intervals. Time-attenuation curves of myocardial enhancement, which were constructed from serial CT images of normally functioning anterior and lateral left ventricular myocardium, demonstrated mean +/- SEM baseline values: 37 +/- 3.3 and 32 +/- 4.0 CT#s; mean +/- SEM peak enhancement: 72 +/- 4.1 and 73 +/- 3.9 CT#s; and decay in enhancement having mean +/- SD time constants: 3.12 +/- 0.27 and 3.17 +/- 0.22 minutes. Regions of acutely ischemic myocardium demonstrated lower but not significantly different baseline values (mean +/- SEM = 25 +/- 4.3 CT#s) from normal (mean +/- sEM = 37 +/- 3.3 CT#s), without a peak and decay in enhancement. The authors conclude that regions of experimentally-produced acute ischemia are readily detected in vivo by dynamic CT imaging as absent or markedly reduced myocardial contrast enhancement.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.