Abstract
A 50-year-old patient demonstrated an acute atypical variant of myelofibrosis characterized by diffuse marrow fibrosis, peripheral myeloblastosis, normal erythrocyte morphology, lack of massive splenomegaly, and a rapidly fatal course. Although this variant is rare in comparison with other myeloproliferative disorders, it deserves recognition. We favor the designation "acute myelofibrosis" for this entity.
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