Acute Lymphoblastic Leukaemia (ALL) with History of Juvenile Idiopathic Arthritis (JIA)

Abstract

Backgrounds: Distinguishing leukemia from Juvenile Idiopathic Arthritis (JIA) is sometimes very difficult. Children with leukemia can also present with complaints of the bones and muscles and many children with leukemia initially present without blast cells in the peripheral blood. Case Reports: A boy aged 8 years 7 months with complaints of joint pain since 6 months before he was admitted to the hospital. Pain was felt intermittently, there was no complaint of fever or bleeding. physical examination, blood pressure 100/70mmHg, pulse 100times/minute, respiratory rate 24times/minute, temperature 36.70C, obtained anemia and splenomegaly. Laboratory tests showed WBC 242.00 x 103/μL, absolute lymphocytes 98.60 x 10 3/μL, RBC 1.54 x 106/μL, HGB 6.02g/dL, PLT 78.09 x 103/μL, CRP 21.65mg/dL, ANA(IF )# negative, RF negative, C3 Complement 150.6mg/dL. Bone Marrow Aspiration (BMA) Acute Lymphoblastic Leukemia (ALL) L2. Conclusion: A boy aged 8 years and 7 months with an initial diagnosis of Juvenile Idiopathic Arthritis, after 3 months of treatment the patient was diagnosed with acute lymphoblastic leukemia based on the results of bone marrow aspiration examination. Currently the patient is undergoing a Leukemia therapy protocol.