Abstract
BackgroundBrucellosis is one of the most widespread zoonoses worldwide. It can affect any organ system, particularly the gastrointestinal system, but there is no report of acute liver failure as a brucellosis complication.Case presentationWe present a case of acute liver failure secondary to brucellosis infection. A 75-year-old Hispanic man presented to a University Hospital in Chía, Colombia, with a complaint of 15 days of fatigue, weakness, decreased appetite, epigastric abdominal pain, jaundice, and 10 kg weight loss. On examination in an emergency room, abdomen palpation was normal with hepatosplenomegaly and the results of a liver function test were elevated. The diagnosis of brucellosis was confirmed by epidemiological contact and positive Rose Bengal agglutination with negative enzyme-linked immunosorbent assay immunoglobulin M for Brucella. He was then treated with doxycycline plus trimethoprim/sulfamethoxazole, with a favorable clinical outcome.ConclusionsThe clinical presentation of brucellosis can be very imprecise because it can affect any organ system; however, there is no report of acute liver failure as a brucellosis complication. This is the first reported case in the Colombian literature of acute liver failure due to brucellosis. We found this case to be of interest because it could be taken into account for diagnosis in future appearances and we described adequate treatment and actions to be taken at presentation.
Highlights
ConclusionsThe clinical presentation of brucellosis can be very imprecise because it can affect any organ system; there is no report of acute liver failure as a brucellosis complication
Brucellosis is one of the most widespread zoonoses worldwide
We present the case of a patient with brucellosis infection secondary to contact with cows from his farm infected with brucellosis
Summary
To the best of our knowledge, this is the first reported case in the Colombian literature of ALF due to brucellosis. ALF is not a common complication of a brucellosis infection. We found this case to be of interest because it could be taken into account for diagnosis in future appearances and we described adequate treatment and actions to be taken at presentation to control the illness and prevent complications and relapses
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