Abstract

A 37-year-old female patient received an IV infusion of iron sucrose injection 200 mg dissolved in 250 ml of 0.9% sodium chloride injection for ectopic pregnancy and mild anemia. About 3 minutes of infusion, the patient suddenly developed laryngeal discomfort and irritating cough. Her symptoms worsened rapidly, dyspnea and cyanosis appeared, oxygen saturation decreased to 0.87, blood pressure was 87/56 mmHg, and heart rate was 121 beats/min. Laryngeal edema induced by iron sucrose injection was considered. Iron sucrose was discontinued immediately, oxygen inhalation and a total dose of dexamethasone 20 mg by IV infusion or IV injection were given. The patient′s symptoms gradually improved. Two hours later, her vital signs were stable and the symptoms disappeared. Key words: Ferric oxide, saccharated; Anaphylaxis; Laryngeal edema

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