Acute kidney injury in snake bite patients

Abstract

Background: In India, large proportion of snake bites occur when people are working barefoot in fields or while walking at night. Objectives: To study i) clinical profile of renal involvement in snake bite patients. ii) in-hospital outcome of acute kidney injury in snake bite patients Methodology: Patients are classified into three stages of acute kidney injury proposed by Acute Kidney Injury Network which defines AKI as an abrupt increase in serum creatinine concentration of ≥0.3 mg/dl from baseline, a percentage increase in the serum creatinine concentration ≥50% or oliguria of 0.5 ml/kg/hr >6 hours. Results: Mean age of patients was 43.8±12.63 years. Male to female ratio was 1.63:1 with male preponderance. Mean interval between snakebite and presentation to hospital was 15.37 hours. All snake bites were inflicted to lower limbs and 48% of snake bites were due to Viper as identified by patients. 98% patients presented with local signs of inflammation. 52% patients presented with coagulation abnormality and 60% with decreased urine output which were associated with increase severity of AKI and need for haemodialysis in 12% of patients.Conclusion: Common manifestations of poisonous snake bite include cellulitis, abnormal Coagulation profile and decreased urine output.