Abstract
Acute kidney injury (AKI) in obstetrics is a serious complication of pregnancy, delivery and the postpartum period, which can have a negative impact on the outcome of pregnancy for both the mother and the fetus. Currently, in developing countries the incidence of AKI during pregnancy and in the postpartum period is 4-26% of all pregnancies, and in the economically developed regions of the world – not more than 2.8%. The frequency of obstetric AKI requiring dialysis is 1:10,000 pregnancies. The causes of kidney injury in pregnant women can be hypertensive disorders, various types of thrombotic microangiopathy (HELLP syndrome, atypical hemolytic-uremic syndrome, thrombotic thrombocytopenic purpura, catastrophic antiphospholipid syndrome), acute fatty liver of pregnancy, obstetric hemorrhages, sepsis and septic shock. The article discusses the diagnostic criteria, biomarkers and timing of development of AKI in pregnancy, the principles of treatment and prevention of this complication in obstetrics.
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