Acute inflammatory demyelinating pseudotumor after COVID-19

T I Yakushina,I O Shtang,D M Yakushin

doi:10.14412/2074-2711-2021-1s-57-61

Abstract

The presence of a single demyelinating focus with signs of the blood-brain barrier (BBB) disruption, revealed during magnetic resonance imaging (MRI), in the absence of clinical symptoms, is most often an accidental finding and requires careful follow-up and anamnesis clarification for diagnosis. Such a focus can be a sign of multiple sclerosis onset, be a symptom of acute disseminated encephalomyelitis, inflammatory demyelinating pseudotumor, brain tumor, encephalitis, etc. Difficulties of differential diagnosis in a radiologically isolated syndrome are reflected in the presented clinical case of a 26-year-old woman who had recovered from COVID-19, in whom an MRI revealed a large single focus in the left frontal lobe with signs of active process.

Highlights

Наличие одиночного фокуса демиелинизации с признаками нарушения целостности гематоэнцефалического барьера (ГЭБ), выявленными при проведении магнитно-резонансной томографии (МРТ), при отсутствии клинической симптоматики чаще всего является случайной рентгенологической находкой и требует тщательного дообследования и уточнения анамнеза для постановки диагноза
The presence of a single demyelinating focus with signs of the blood-brain barrier (BBB) disruption, revealed during magnetic resonance imaging (MRI), in the absence of clinical symptoms, is most often an accidental finding and requires careful follow-up and anamnesis clarification for diagnosis. Such a focus can be a sign of multiple sclerosis onset, be a symptom of acute disseminated encephalomyelitis, inflammatory demyelinating pseudotumor, brain tumor, encephalitis, etc
Difficulties of differential diagnosis in a radiologically isolated syndrome are reflected in the presented clinical case of a 26-year-old woman who had recovered from COVID-19, in whom an MRI revealed a large single focus in the left frontal lobe with signs of active process

Summary

Introduction

Наличие одиночного фокуса демиелинизации с признаками нарушения целостности гематоэнцефалического барьера (ГЭБ), выявленными при проведении магнитно-резонансной томографии (МРТ), при отсутствии клинической симптоматики чаще всего является случайной рентгенологической находкой и требует тщательного дообследования и уточнения анамнеза для постановки диагноза. ПЭТ головного мозга, совмещеной и прицельно гипофиза пациентки С. Графией (ПЭТ-КТ), МРТ головного мозга с контрастом в динамике через а – T2 FSE, FLAIR; b – T1 FSE, FLAIR

Results

Conclusion