Abstract
THE majority of people, about 70 per cent, experience their first infection with the herpes simplex virus in infancy or early childhood. This infection is usually inapparent, and can therefore only be recognized as having occurred by the presence of circulating antibodies.1 However, in about 1 per cent of all infections, the first attack of the virus can give rise to a serious or even fatal disease. These primary infections, of which the commonest is the clinical entity known as acute herpetic gingivostomatitis,2 3 4 5 6 are well recognized in childhood because they commonly occur in this age group. In adult life, however, . . .
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