Abstract

Two premature female infants had severe hyperbilirubinemia caused by hemolysis. Both neonates were heterozygotes for the glucose-6-phosphate dehydrogenase Mediterranean mutation as determined by DNA analysis. Glucose-6-phosphate dehydrogenase–deficient heterozygotes may be susceptible to the complications of this enzyme deficiency. (J Pediatr 2001;139:137-40)

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