Acute gouty arthritis attacks induced by a great toe injury: a case report and literature review

Abstract

Introduction: Gouty arthritis usually occurs in patients with hyperuricemia and can be induced by a variety of factors. Here, we describe a case of acute gouty arthritis attacks induced by a great toe injury and was successfully treated by benzbromarone and ibuprofen. Patient concerns: A 27-year-old Asian man with hyperuricemia informed us his first metatarsophalangeal joint of left foot began to redness and swelling, accompanied by severe pain presented 8 days after the toenail injury. Diagnoses: Laboratory tests confirmed as gouty arthritis with no signs of infection, but serum uric acid was significantly higher than normal at 523 μmol/L. Interventions: Drug treatment was adopted, including benzbromarone 100 mg daily, ibuprofen pills 75mg twice a day, and sodium bicarbonate tablets 0.5g three times a day. Outcomes: All of his symptoms of acute gouty arthritis attacks gradually disappear after drug treatment for a week and blood uric acid had dropped to 87 μmol/L two weeks later. Conclusion: When patients with a broken great toe present with symptoms of first metatarsophalangeal joint began to redness and swelling, accompanied by severe pain, acute gouty arthritis attacks should also be considered, and the drug treatment is effective. Abbreviation: GA = Gouty arthritis, MSU = Monosodium urate, ESRD = End-stage renal disease.