Abstract
Methods and Materials: Mucosa hyperplasia is an uncommon cause of gastric outlet obstruction in neonatal period. The main etiologic factor of this disorder is long-term prostaglandin E1 (PGE1) infusion. PGE1 administration is used to maintain the patency of the ductus arteriosus in neonates with ductal-dependent cyanotic congenital heart diseases. The treatment although life saving is limited with possible side effects. The pathophysiology of prostaglandin induced gastric mucosa hyperplasia is based on delayed senescence and exfoliation of foveolar cells. Supposition of this disorder is possible on the basis of some clinical features, results of chest radiographs, contrast gastrointestinal imaging or ultrasound examination. We present two cases of neonates with tetralogy of Fallot, pulmonary trunk hypoplasia and PDA hospitalised in Pediatric Cardiology Departament of Medical University in Gdansk, for who prostaglandin E1 therapy was started on the second day of life. After around 3–3,5 weeks of these treatment clinical features of acute gastric outlet obstruction were noticed. Therefore ultrasound examination was carried out using Unit GE Logiq 500, with microconvex transducer 3–7MHz and linear transducer 8,2–11,0MHz.
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Schedule a callMore From: Ultraschall in der Medizin - European Journal of Ultrasound
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